Mushroom “Vitamin ɗin Dogon Rayuwa” Ya ƙara NAD+ a Berayen Tsohuwa Ta Hanyar H2S
Ergothioneine, sinadarin ƙwaro da ake kira “vitamin ɗin dogon rayuwa,” ya nuna sabuwar hanya da ke haɗa ƙaruwa da ƙara NAD+. A wani bincike da aka wallafa a Cell Metabolism, berayen da suka tsufa kuma aka ba su ET sun samu ƙarin juriya a treadmill, ƙara ƙarfi a tsoka, da hauhawar matakin NAD+. An gano cewa tasirin ya ta’allaka ne da hanyar hydrogen sulfide wadda ke haɗa CSE, persulfidation, da enzyme cGPDH. Idan an cire CSE ko cGPDH, wadannan fa'idodi sun ɓace. Koyaya, binciken an yi shi ne a dabbobi da dakin gwaje‑gwaje, kuma adadin da aka yi amfani da shi a berayen ya kai kusan sau 10 na abin da aka saba samu a ƙwayoyin ƙaruwa.
Rapamycin Sau Daya a Kowane Mako na Shekara: Lafiya, Amma Shin Kitse na Ciki Ya Sauya?
Kowa na son sanin ko shan rapamycin sau ɗaya a mako zai rage kitse a cikin ciki kuma ya ƙara tsawon lokacin lafiya. Gwajin PEARL ya ba da amsoshi masu ban mamaki: bayan makonni 48 da aka yi wa manya masu lafiya, ba a ga wani canji a adadin kitse na ciki ba, kuma amincin maganin ya yi kama da na placebo. Wasu alamu na biyu – kamar ƙaruwa a ƙwayar ƙiba da rage radadi a mata masu sha 10 mg, da kuma jin daɗi mafi kyau a ƙungiyar 5 mg – suna nuna yiwuwar fa'ida, amma sakamakon na ƙananan rukuni ne kuma ba su tabbatar da tsawaita rayuwa ba. Ga abin da aka samu da abin da ba a samu ba.
Calcium Alpha‑Ketoglutarate Ya Kara Tsawon Rayuwar Berayen Mata Har Zuwa 16.6% – Menene Ake Nufi Da Abin Da Ba A Nufi Ba?
Binciken da aka wallafa a mujallar *Cell Metabolism* (2020) ya nuna cewa ciyar da berayen da suka kai tsakiyar shekarunsu da abincin da ke ɗauke da 2 % calcium alpha‑ketoglutarate (CaAKG) ya ƙara wa mata tsawon rai har zuwa 16.6 % kuma ya rage kamuwa da rauni. Amma sakamakon ya shafi beraye ne kawai, ba ya nufin zai yi tasiri iri ɗaya a jikin ɗan adam ba.
Taurine, Sinadarin Amino Mai Araha da Ya Tsawaita Rayuwar Kunkuru da Kusan 12% Kuma Yana Raguwa da Yawan Taurine a Jinin Mutane
Binciken *Science* na 2023 ya gano cewa matakin taurine a jini – sinadarin amino mai araha da ake samu a ko'ina – yana raguwa da tsufa a cikin kunkuru, birai da mutane. Sa ran taurine ga kunkuru a tsakiyar rayuwa ya ƙara musu tsawon rai da kusan kashi 10‑12% tare da inganta lafiyarsu gaba ɗaya. An ga taurine na rage alamun tsufar ƙwayoyin, lalacewar DNA, matsalolin mitochondria da kumburin da ake kira “inflammaging”. Duk da haka, hujjojin daga mutane na ƙalla‑kalla ne, kuma ƙididdigar da aka samu a kunkuru tana nufin gram‑grama da yawa a kullum. Saboda haka masana sun ƙara jaddada buƙatar ƙarin gwaje‑gwaje kafin a ɗauki taurine a matsayin maganin tsufa.