Hydrogen Water Backfired: Oxidative Damage Marker Rose in Trial
Hydrogen-rich water is marketed as an easy antioxidant win, but a randomized, blinded trial in people with chronic mountain sickness found the opposite signal. After 8 weeks of 990 mL/day, the hydrogen group's MDA, a marker of oxidative damage, rose more than placebo's, by +2.11 (p < 0.001). Total antioxidant capacity rose too, and the MDA increase was larger in people with a BMI of 24 or higher. Adverse events were more common with hydrogen water (50% vs 37%), mostly dizziness. The study was small and specific to altitude patients, so here is what it does and doesn't mean for hydrogen water fans.
Vitamin C and E Linked to 18% Lower Alzheimer Risk, With a Catch
In the Rotterdam Study of 5,395 older adults, higher dietary vitamin C and vitamin E intake were each linked to roughly 18% lower Alzheimer risk per standard deviation. The pattern looked strongest among smokers, where beta carotene and flavonoids also stood out. But this was an observational study of food intake, not pills, so it shows association rather than cause. Some of the headline smoker numbers also have confidence intervals that cross 1.0. Here is what the data actually say, which foods supply these nutrients, and where supplements do and do not fit.