#biohacking

2 articles

Approach: conceptual metaphor. Palette: bold color field.

A single steel bathroom-style analog tape measure, pulled taut and wrapped around a ripe, glossy yellow-orange pear lying on its side, with the tape's tip locked at the same unmarked point, suggesting a waistline that did not shrink. The pear sits on a saturated magenta seamless backdrop, shot from a low three-quarter angle with a shallow depth of field, the stem sharp and the background softly blurred. Hard but slightly diffused studio key light from upper left casts a crisp, short shadow in deeper magenta on the surface. A tiny electric green sticky dot marks the tape's end, with no numbers or writing visible. Mood: playful, skeptical, deadpan, scientific restraint rather than hype.

Tjedni rapamicin tijekom godine: siguran, ali je li smanjio visceralnu mast?

BY REX MERIDIAN · 16. lis 2026.

Zanima li vas može li tjedni rapamicin smanjiti visceralnu mast i poboljšati zdravlje? Studija PEARL donosi iznenađujuće odgovore. Nakon 48 tjedana primijenjenog liječenja na zdravim osobama, primarni ishod – visceralna mast – nije pokazao promjenu, iako je profil sigurnosti bio sličan placebo grupi. Neki sekundarni pokazatelji, poput povećanja mišićne mase i smanjenja boli kod žena na 10 mg te boljeg osjećaja dobrobiti na 5 mg, upućuju na moguće koristi. Međutim, ti podaci su podskupinski i samoprijavljeni, lijek je bio pripremljen po mjeri, a nitko još nije dokazao da produljuje ljudski životni vijek. Evo što studija zaista pokazuje, a što ne.

**Approach: Conceptual metaphor. Palette: B, Warm.**

A close, slightly high three-quarter view of a single weathered hemp rope stretched horizontally across the frame, shot at a shallow depth of field. On the left the rope is thick and tightly twisted. On the right it has frayed down to a few thin strands, with a short, neat whipping of bright electric green thread binding the rope just where the fraying stops. Golden-hour sunlight enters low from the left and picks out each individual fiber in honey and copper tones. Soft amber shadows fall across a blurred, sun-warmed wooden dock in the background. The mood is quiet and cautiously hopeful, suggesting something worn down slowly but partly held in place. The image is photorealistic and has no text.

longevity

Vitamin D3 usporio skraćivanje telomera za 140 baznih parova u četverogodišnjem randomiziranom kontroliranom ispitivanju

BY DR. SYNAPSE · 15. lis 2026.

Veliko, randomizirano, placebom kontrolirano ispitivanje otkrilo je da četiri godine suplementacije vitaminom D3 usporavaju skraćivanje telomera za otprilike 140 baznih parova. Podaci potječu iz VITAL studije na starijim odraslim osobama u SAD‑u koje su uzimali 2 000 IU dnevno. Učinak je skroman i na granici značajnosti (p = 0,039), a duljina telomera je samo surrogatni biomarker, ne dokaz dužeg života. Omega‑3 masne kiseline u istom ispitivanju nisu pokazale učinka na telomere.