#oxidative-stress

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Approach: Macro science. Palette: D, bold color field.

Extreme close-up microscopy-style photograph of a stained rat skeletal muscle cross-section, shot straight down through the microscope objective. Polygonal muscle fibers fill the frame in saturated magenta and pink eosin tones. A cluster of fibers on the left is neatly packed and uniform. On the right, the tissue is disrupted, with swollen gaps and thin, fibrous collagen strands in pale violet threading between damaged cells. A few tiny electric green fluorescent specks sit along one fiber edge as a subtle accent. Lighting is bright, even transmitted light with crisp focus at the center and soft falloff at the edges. The mood is analytical and tense, a rescue only partly complete. No text, no labels.

BPC‑157 保护大鼠肌肉免受缺血‑再灌注损伤——细节值得关注

BY NOVA CHEN · 2026年11月1日

在血流被切断后再次快速恢复供血时，组织往往会因再灌注而受到更严重的二次损伤。最新的大鼠实验显示，缺血结束时给药的 BPC‑157 能降低氧化应激、抑制凋亡、减轻炎症并部分恢复 VEGF 水平，肌肉结构更完整、胶原沉积减少。但该研究每组仅 6 只大鼠、只做一次腹腔注射（20 µg/kg），再灌注观察时间仅 2 小时；BPC‑157 仍未获批准，研究结果仅限动物实验，不能直接用于人类。