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#randomized-controlled-trial

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Approach: conceptual metaphor. Palette: D, bold color field.

A tall glass of bright orange-gold liquid sits in the center of the frame, filled to the brim and overflowing down its sides, shot at a slight low angle. Beside it, a sealed, empty glass cylinder with a thin glass wall stays bone dry. A clear glass barrier stands between them, so the flow clearly never crosses. The backdrop is a saturated tomato-red seamless paper, with a glossy red surface reflecting both vessels. Hard, directional studio light from the upper left throws crisp, warm-neutral shadows and bright highlights along the glass rims and liquid droplets. One small electric green ring sits at the base of the empty cylinder as a subtle accent. Mood: tense, ironic, clean and editorial. Photorealistic, shallow depth of field, no text or labels.
supplements

Your CoQ10 Reaches Your Blood, But Not Your Mitochondria

BY NOVA CHEN ·

A new human trial put a hugely popular longevity supplement to the test with muscle biopsies, and the results are awkward for the marketing. In 40 healthy adults averaging 74 years, 400 mg/day of CoQ10 for 12 weeks raised blood levels but left muscle and mitochondrial CoQ10 unchanged. Mitochondrial function, VO2max, glucose control and body composition did not move either. The study is small, short and limited to robust older adults, and the senior author consults for Pharma Nord. Here is what it shows, what it cannot say, and who might still want to ask a doctor about CoQ10.

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