#prolon

1 article

Approach: conceptual metaphor. Palette: D, bold color field.

Subject: a single old-fashioned mechanical light switch, photographed straight on, with its toggle stuck halfway between on and off. It is mounted on a saturated mustard-yellow painted wall. A thin electric green (#00e676) glow leaks from the gap behind the toggle and casts a small green rim onto the plate. Beside it, a row of six small matte black tally marks is scratched into the paint, with the third and fifth marks fainter and partly worn, hinting at inconsistent results across days.

Camera: slightly low, eye-level angle with a 50mm lens, shallow depth of field, and the switch placed on the right third of the frame.

Lighting: hard directional side light from the left casts crisp, warm-neutral shadows with no blue cast. The wall texture and brushstrokes are visible.

Mood: curious, skeptical, and measured. The scene suggests a mechanism that is partly engaged.

Fasting-Mimicking Diet Nudged Human Autophagy—But Not Every Time

BY HELIX WARD · Nov 1, 2026

Does the fasting-mimicking diet really switch on autophagy in people, or only in mice? A new pilot randomized trial in 30 healthy adults tested ProLon and a second FMD formulation against control. By the end of the roughly 6-day diet, the groups differed in autophagic flux, weight, glucose, ketones, and insulin resistance. But those differences did not hold at every time point, and the trial was small and sponsored by ProLon's maker. Here is the protocol, what it showed, and who should think twice.