A new network meta-analysis of 27 studies and 1,599 adults compared NMN, NR, NADH and nicotinamide, and the results are not what supplement marketing promises. NMN showed a dose-dependent boost in endurance, with a standardized mean difference of 1.02 at the high dose. NADH led for cognition, but mostly in cognitively impaired groups and with a result sensitive to influential studies. The surprise is that no precursor significantly improved perceived fatigue or sleep. Here is how the ranking breaks down, what the limits are, and who should or shouldn't bother.
This page is available in