Your CoQ10 Reaches Your Blood, But Not Your Mitochondria
A new human trial put a hugely popular longevity supplement to the test with muscle biopsies, and the results are awkward for the marketing. In 40 healthy adults averaging 74 years, 400 mg/day of CoQ10 for 12 weeks raised blood levels but left muscle and mitochondrial CoQ10 unchanged. Mitochondrial function, VO2max, glucose control and body composition did not move either. The study is small, short and limited to robust older adults, and the senior author consults for Pharma Nord. Here is what it shows, what it cannot say, and who might still want to ask a doctor about CoQ10.
Two Cheap Supplements Cut Heart Deaths by Half. There's a Catch.
Two inexpensive supplements, CoQ10 and selenium, were linked to a drop in cardiovascular deaths from 12.6% to 5.9% in elderly Swedes. Heart-strain biomarkers and echocardiograms improved as well. But the trial enrolled just 443 people in a selenium-poor country, and it can't say which nutrient did the work. Here's what the KiSel-10 study actually showed, who it may apply to, and the safety limits to know before you try it.