#pulse wave velocity

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Magnesium Eased Stiff Arteries After 6 Months—Then Came a Null Trial

BY DR. SYNAPSE · Oct 29, 2026

For 12 weeks, magnesium did nothing measurable to arterial stiffness. At week 24, a 52-person randomized trial found pulse wave velocity improved by 1.0 m/s versus placebo, with no change in blood pressure. It's an eye-catching result for anyone interested in vascular aging. But a larger 2022 follow-up from the same group, testing 164 adults and three magnesium forms, found no significant effect. Here's what the original study showed, where it falls short, and what to make of the conflicting evidence.