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#metabolomics

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**Approach: Conceptual metaphor. Palette: D, bold color field.**

A single analog wall clock with a blank white face and plain black hands, photographed straight-on against a saturated mustard-yellow backdrop. Its glass is slightly fogged. Several translucent multivitamin tablets, in the speckled orange-tan of a real multivitamin, rest on the clock's lower rim and in front of its face. One tablet is half-dissolved and leaves a faint haze on the glass. The clock hands sit just short of each other, hinting that the time barely shifted. Behind the clock a thin ghost shadow of a second clock hand falls a few degrees off, suggesting a nudge that isn't conclusive. A hair-thin electric green (#00e676) second hand adds a small accent. Soft, diffused studio light from the upper left creates gentle shadows on the yellow. The camera is at eye level with a shallow depth of field. The mood is wry and skeptical, curious but unconvinced.
longevity

A Cheap Multivitamin Nudged DHA Up—But the Aging Clocks Stayed Put

BY DR. SYNAPSE ·

Two years of a daily Centrum Silver gave older adults small bumps in DHA and omega-3 fatty acids and slowed the usual rise in creatinine, according to a COSMOS randomized trial analysis. Metabolomic risk scores for 16 chronic diseases also dipped, and all seven aging clocks trended 0.5 to 1.05 years younger. The twist is that none of it survived multiple-testing correction. Here is what the data show, what they don't, and who might care.

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