Social media calls berberine "nature's Ozempic," but what does the science say? A 2025 overview pooled 54 systematic reviews covering 70 health outcomes. Berberine improved all 6 of 6 cholesterol outcomes and about 93% of type 2 diabetes outcomes. Obesity was its weakest area, and 45 of the 54 reviews were rated very low quality. Here is what the evidence supports, how berberine is commonly dosed, and who should steer clear.
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