#frailty

1 article

Approach: the human outcome. Palette: natural.

A tight, low-angle shot of an elderly person's hands gripping a smooth wooden cane at the top of a sunlit garden path. The hands are weathered and slightly tremulous, with visible veins and thin, spotted skin. Behind them, the blurred figure of a seated older man in a cardigan is just recognizable, with his face out of frame. Warm late-morning daylight comes from the side and picks out the grain of the wood and the texture of the skin. The background is soft green foliage and a gravel path in shallow depth of field. The tones are plant greens, honeyed wood and natural skin. A single fresh leaf in vivid electric green sits in the lower foreground. The mood is quiet, honest and reflective, and it suggests fragility without drama.

Stariji s frahlijom imali su niži NAD+ u krvi – što to znači za NMN i NR

BY HELIX WARD · 26. lis 2026.

Novi rad u časopisu *GeroScience* na 529 starijih Japana otkriva da su osobe s frahlijom imale neznatno niže razine NAD+ u krvi, s otprilike 13 % manjim rizikom po svakom povećanju od 1 µmol/L. Studija je poprečnog dizajna, obuhvatila je samo 32 frahlija, a razlika u medianama iznosila je jedva 24 vs 25 µmol/L. Veza se dodatno oslabila nakon podešavanja za hematokrit, što upućuje da sastav krvnih stanica može objasniti dio rezultata. U nastavku objašnjavamo što podaci zaista znače, zašto ne dokazuju da NMN ili NR sprječavaju frahliju i što treba uzeti u obzir ako razmišljate o NAD‑prekurzorima.