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supplements

1,000 mgのニコチン酸リボシドを毎日摂取すると、高齢者の血液細胞NAD+が約60%上昇 – ランダム化比較試験の結果

BY DR. SYNAPSE ·

2018年に『Nature Communications』で報告されたクロスオーバー試験では、健康な中高年者を対象にニコチン酸リボシドを1日1,000 mg(500 mgを2回)6週間投与しました。サプリは耐容性が良好で、血液中の免疫細胞におけるNAD+がプラセボ比で約60%上昇しました。血圧低下や動脈硬化の初期的なシグナルも観察されましたが、これは大規模試験用の仮説であって確立された効果ではありません。本記事では、NAD+が加齢とともに減少すると考えられる理由、研究の概要、そして疾病予防や長寿への示唆について解説します。

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