Biocracked
**Approach:** Conceptual metaphor. **Palette:** Bold color field (teal).

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Longevity

Magnesium Na Rage Tsaurin Jijiyoyin Jini Bayan Watanni 6 – Kwarin Gano Da Ba a Tabbata ba

Dr. Synapse · · 5 min read

Magnesium Na Rage Tsaurin Jijiyoyin Jini Bayan Watanni 6 – Kwarin Gano Da Ba a Tabbata ba

Excerpt: A cikin wata 12, magnesium ba ta yi tasiri a iyaka kan ƙarfafa jijiyoyin jini ba. A makon 24, wani gwaji mai tsari da ya haɗa mutane 52 ya gano cewa saurin gudun bugun jini ya sauka da 1.0 m/s idan aka kwatanta da placebo, ba tare da wani canji a hawan jini ba. Wannan sakamako na ɗaukar hankali ga duk wanda ke sha’awar tsufar jijiyoyi, amma wani babbar bincike da ke da mutane 164 da nau’o’in magnesium guda uku ba ya ba da irin wannan tasiri. Don haka hujjar da ake da ita har yanzu alama ce da ke buƙatar ƙarin bincike.

Binciken: Ƙarami, An Iya Sarrafa Shi, Kuma An Rufe Da Kyau

Wannan takarda, da aka wallafa a American Journal of Clinical Nutrition ta Joris da abokan aikinsa daga Jami'ar Maastricht, ta bayar da rahoton gwajin da ya ɗauki makonni 24, an tsara shi a matsayin gwajin rufe‑placebo. An zaɓi mutane 52 da suke da nauyi ko ƙasa‑ƙasa‑kaso: maza 30 da mata 22, matsakaicin shekaru 62 (± 6) kuma suna da tarihin hawan jini.

Masu shiga gwajin sun sha kwayar magnesium ko placebo sau uku a rana. Ƙungiyar magnesium ta karɓi 3 × 117 mg (kimanin 350 mg a kowace rana). Takaitaccen bayanin bai bayyana wane salo na magnesium aka yi amfani da shi ba, don haka ba za mu iya yin hasashen ba.

Matsayin farko da aka auna shi ne carotid‑to‑femoral pulse wave velocity (PWVcf), wanda aka auna a farkon gwaji, a mako na 12 da kuma a mako na 24. Wannan ma’auni ana amfani da shi sosai a matsayin alamar tsaurin jijiyoyin jini. Saurin bugun jini yana ƙaruwa idan jijiyoyi sun yi tsauri, kuma tsaurin jijiyoyi yana ƙaruwa da tsufa. Ƙungiyar ta kuma tara fitsari na sa’o’i 24 da auna hawan jini na minti 24 a farkon da ƙarshen gwajin.

Sakamakon Da Ya Ja Hankali: Raguwar 1.0 m/s, Amma Kawai A Mako Na 24

Mako 12 – Bambanci a PWVcf tsakanin magnesium da placebo shi ne 0.0 m/s (95 % CI = ‑0.6 zuwa 0.5; P = 0.90). Babu tasiri.

Mako 24 – PWVcf ya ragu da 1.0 m/s a ƙungiyar magnesium idan aka kwatanta da placebo (95 % CI = 0.4 zuwa 1.6; P = 0.001).

Wannan yana nufin fa’idar ba ta bayyana a farkon gwajin ba; sai a tsakiyar lokacin gwajin. Irin wannan yanayi ya dace da fahimtar cewa canjin tsaurin jijiyoyi wani al’amari ne da ke buƙatar lokaci mai tsawo don bayyana, ba wani abu da za a ga a cikin ‘yan makonni ba. Binciken ba ya iya fayyace dalilin da ya sa tasirin ya bayyana a mako na 24, kuma marubutan suna kiran wannan alama ce ta yiwuwar hanyar aiki, ba hujjar ƙarshe ba.

Abubuwan Da Ba Su Canza Ba (Kuma Me Ya Sa Wannan Yake Muhimmi)

  • Hawan jini bai canza ba. Ba a ga wani sauyi a hawan jini a ofis ko a cikin sa’o’i 24 ba. Idan magnesium tana sassauta jijiyoyi, ba lallai take haifar da sauƙin ragin hawan jini ba, duk da yadda wasu ke tsammani.
  • Matakin magnesium a cikin serum bai ƙaru sosai ba. Serum magnesium ya ƙaru da 0.02 mmol/L a mako na 24 (95 % CI = 0.00‑0.04; P = 0.09), wanda ba shi da ma’ana a ƙididdiga. Fitsarin magnesium a cikin fitsari ya ƙaru da 2.01 mmol a kowace rana (P < 0.001), alamar cewa an shige da kwayar da aka sha. Serum magnesium ba alamar jimillar magnesium a jiki ba, don haka ba za a iya danganta sauyin PWV da canjin serum ba.
  • Babu rahoton haɗari.

Guguwa Ta Biyo Baya: Binciken Mafi Girma Ya Gano Babu Tasiri

Idan labarin ya tsaya a nan, za mu samu “maganin tsawaita rai”. Amma gwajin da aka gudanar daga ƙungiyar guda ɗaya (Schutten et al., 2022, Journal of the American Heart Association, PMID 35253448) ya haɗa mutane 164 masu nauyi ko ƙasa‑kaso. An gwada magnesium citrate, oxide, da sulfate a 450 mg a rana na tsawon makonni 24, an kwatanta da placebo. Babu wani tasiri mai ma’ana kan PWV ko hawan jini.

Binciken biyu sun bambanta a cikin ƙimar magani, nau’in magnesium, da yawan mahalarta, don haka ba za a iya haɗa su ba. Sabon binciken, wanda ya fi girma kuma ya gwada nau’o’in magnesium da dama, bai maimaita sakamakon 2016 ba. Don haka, sakamakon farko yana nuni ne da alamar da ke buƙatar ƙarin bincike, ba hujja tabbatacce ba.

Ƙuntatawa Da Ya Kamata Ka San

  • Ƙananan ƙungiya: Mutane 52 ba su isa ba don samun ƙarfi a ƙididdiga.
  • Wanda aka yi wa gwaji: Mutane masu shekaru 62 da suka yi kiba ko ƙasa‑kaso. Sakamakon na iya bambanta a matasa, marasa kiba, ko mutanen da ba su da cutar zuciya.
  • Alamar da aka auna: PWV alama ce da ke danganta da haɗarin cutar zuciya, ba ma’aunin bugun zuciya ko tsawon rai ba. Binciken bai tsara don duba tasirin a kan waɗannan sakamakon ba.
  • Ba a maimaita ba: Binciken na baya bai tabbatar da tasirin ba.
  • Ba a bayyana nau’in magnesium ba: Takaitaccen bayanin bai nuna wane salo aka yi amfani da shi ba.

Abubuwan Da Za Ka Iya Amfani Da Su

  • Abin da aka gwada: Kimanin 350 mg na magnesium a rana, an raba zuwa kashi uku na kusan 117 mg, na tsawon makonni 24. Idan akwai fa’ida, a cewar wannan gwaji, za ta bayyana ne bayan watanni shida; gwaje‑gwajen gajere ba za su nuna cikakken sakamako ba.
  • Wanene zai iya sha’awarsa: Mutanen da ke tsakiyar ƙuruciya (50‑60 shekara), masu kiba, kuma da niyyar ƙara lafiyar jijiyoyi. Duk da haka, hujjojin suna da takamaiman iyaka, kuma magnesium ba zai iya maye gurbin hanyoyin da aka tabbatar ba kamar motsa jiki, sarrafa nauyi, rage hawan jini, da cin abinci mai wadatar magnesium (wake, gyada, ganyen kale, da sauransu).
  • Waɗanda ya kamata su yi hattara: Mutanen da ke da matsalar koda ko masu shan magungunan zuciya su nemi shawarar likita kafin ƙara magnesium. Ƙarin magnesium na iya haifar da matsalolin narkewa, kuma 350 mg a rana shi ne iyaka da aka amince da ita a Amurka.

Gabaɗaya

Wani ƙananan gwaji da aka yi da kyau ya nuna raguwar tsaurin jijiyoyi bayan watanni shida na shan magnesium, ba tare da canjin hawan jini ba kuma babu haɗari. Binciken mafi girma ba ya ba da irin wannan sakamako. Ka ɗauki magnesium a matsayin wani kayan gina jiki da ke da amfani amma ba a tabbatar da tasirinsa a kan tsufar jijiyoyin jini ba, kuma ba zai maye gurbin hanyoyin da aka tabbatar ba.

Original study

Read the original research on pubmed.ncbi.nlm.nih.gov →

This article summarizes published research for general information. It is not medical advice.

DS

Written by

Dr. Synapse

Dr. Synapse writes for Biocracked: biohacking science, longevity & human performance.

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