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metabolism

Prvi ljudski uspjeh NMN‑a: 250 mg dnevno povećalo osjetljivost mišića na inzulin za oko 25 % kod predijabetičkih žena

BY DR. SYNAPSE ·

NMN je dugo bio zvijezda trenda za dugovječnost, ali dokazi na ljudima bili su oskudni sve dok nije objavljena studija Washington Universityja u časopisu *Science* 2021. godine. Kod žena u postmenopauzi s predijabetesom i prekomjernom tjelesnom težinom ili pretilošću, 250 mg NMN‑a dnevno tijekom 10 tjedana poboljšalo je osjetljivost mišića na inzulin za otprilike 25 %. Signali inzulina u mišiću i geni povezani s remodeliranjem mišića također su se poboljšali, dok u grupi s placebom ništa nije promijenjeno. Međutim, korist je bila ograničena i studija nije pokazala da NMN snižava razinu šećera u krvi ili preokreće predijabetes. Evo što je studija otkrila, na koga se odnosi i što nije promijenila.

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